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 JUDITH L. RAPOPORT, M.D

Education:B.A., Swarthmore CollegeM.D., Harvard University

Positions Held:

1984‑present Chief, Child Psychiatry Branch National Institute of Mental Health Bethesda, Maryland
1982‑1984 Chief, Section on Child Psychiatry
Laboratory of Clinical Science National Institute of Mental Health
Bethesda, Maryland

1979‑1982 Chief, Unit on Childhood Mental Illness Biological Psychiatry Branch
National Institute of Mental Health Bethesda, Maryland

1985‑present Clinical Professor of Psychiatry & Pediatrics Georgetown University Medical School Washington, D.C.

1979‑present Professor of Psychiatry George Washington University School of Medicine Washington, D.C.

1976‑1978 Medical Officer, Unit on Childhood Mental Illness Biological Psychiatry Branch National Institute of Mental Health Bethesda, Maryland

1974‑1975 Principal Investigator: Effect of ACTH 4‑10 on Attention and Cognitive Functioning in Hyperactive Children Grant from Organon, Oss, The Netherlands

1974‑1976 Co‑Investigator, Easter Seal Grant: Minor Physical Anomalies and Early Developmental Deviation

1971‑1976 Principal Investigator: Biological Factors in Hyperactivity, HEW PHS Grant #MH20802

1972‑1982 Clinical Assistant Professor of Pediatrics & Psychiatry Georgetown University Medical School Washington, D.C.

1969‑1972 Consultant Child Psychiatrist National Institute of Mental Health St. Elizabeth's Hospital Division of Training & Manpower Washington, D.C.

1967‑1970 Consultant Child Psychiatrist National Institute of Child Health & Development Bethesda, Maryland

1966‑1972 Staff Psychiatrist, "P" Street Clinic Department of Public Health Washington, D.C.

1966‑1967 NIMH Special Fellowship, Laboratory of Psychology National Institute of Mental Health Bethesda, Maryland

1964‑1966 Child Psychiatric Training Program (NIMH) Fellowship in Child Psychiatry Department of Psychiatry Children's Hospital Washington, D.C.

1962‑1964 NIMH Postdoctoral Fellowship Psychological Institute Upsala, Sweden and Karolinska Hospital, Stockholm, Sweden

1961‑1962 Psychiatric Residency St. Elizabeth's Hospital Washington, D.C.

1960‑1961 Psychiatric Residency Massachusetts Mental Health Center Boston, Massachusetts

1959‑1960 Internship (rotating) Mt. Sinai Hospital New York, New York

Honors, Awards, and Fellowships:

Phi Beta Kappa
B.A., Magna Cum Laude, Swarthmore College, 1955
Chairman, Advisory Committee on Neuropsychotropic Agents, FDA, 1981‑1982
Member, Childhood and Adolescents Committee, American Psychiatric Association, Task Force on Statistics and Nomenclature, 1975-Present
Veiga Lecture in Child Psychiatry, Baltimore, 1979
Semrad Memorial Lecture, Boston, 1981
Ittleson Research Prize, American Psychiatric Association,1983
Public Health Service, Superior Service Award 1987
Voorsanger Lectureship, Stanford University 1987
Taylor Manor Psychiatric Research Award, 1988
Academic Psychiatry Consortium: Center for Advanced Study in the Behavioral Sciences, 1988-1991.
NIMH Directors Award, 1990
Sachar Award, Columbia University, 1990
Winkelman, Award, University of Pennsylvania, 1990
Presidential Meritorious Executive Rank Award, 1991
Committee to Visit the Harvard Medical School and School ofDental Medicine, 1992 to 1998
President, Society for Research on Child and AdolescentPsychopathology, 1991
American Psychiatric Association Award for Research, 1992
Gertrude Rogers Memorial Lecture, UCLA, 1992
G. Burroughs Mider Lecture, NIH, 1993
Member, Institute of Medicine, 1993
Distinguished Service Award, 1993
Gundry Lecture, University of Maryland, 1994
Weissman Lecture, Pennsylvania Hospital, 1995
Mysell Lecture, Harvard University, 1996
Jones Lecture, Dalhousie University, 1996
Invited Lecture: Centennial Celebration,Columbia University School of Medicine, October 1996
Stanley Conn Lecture, Department of Pharmacology, George Washington University, Washington, D.C. Nov 1996
President, American Psychopathological Association, 1998
American Psychiatric Association Research Prize, 1999 Fellow - American Academy of Arts and Sciences 2000 -
Invited Lecture - Kanner Lecture, Johns Hopkins, June 2001
Yarborough Lecture - Cornell Univ. School of Medicine, 2001
Invited plenary speaker, Society for Neurosciences,
San Diego CA, November 2001

Distinguished Service Award – American PsychiatricAssociation, 2002

McGavin Award for Prevention in Child Psychiatry, 2002

Ruaner Research Prize – NARSAD, 2002

Editorial Boards:

Member of Editorial Boards:
Advances in Clinical Child Psychology: 1983‑Present
American Journal of Psychiatry: 1983‑Present
Journal of Abnormal Child Psychology: 1983‑Present
Journal of the American Academy of Child Psychiatry:1979‑1982, 1985‑Present
Journal of Child Psychology and Psychiatry and AlliedDisciplines, 1984‑Present,
Journal of Psychiatric Research: 1982‑Present
Psychiatry Research: 1979‑Present;
Associate Editor, Psychopharmacology Bulletin, 1982‑1997
Book Review Editor, Journal of the American Academy of Child Psychiatry, 1982‑1984
Member, Editorial Board: Archives of General Psychiatry, 1992; Biological Psychiatry, 1987–Present; Journal ofChild and Adolescent Psychopharmacology, 1998-Present

Licensure: Washington, D.C., 1961

Board of Certification:
American Board of Psychiatry & Neurology, April 1969
American Board of Child Psychiatry, September 1969

Membership in Professional Associations:
American Academy of Child Psychiatry (Fellow)
American Psychopathological Association (Fellow)
American Psychiatric Association (Fellow)
American College of Neuropsychopharmacology (Fellow)

Board Memberships

Foundation for Advanced Education in the Sciences, NIH,
1987-Present; Board Member National Anxiety Foundation-Scientific Advisory Board Psychiatric Research Society
Scientific Advisory Board:Tourette’s Syndrome Association,(1988-1993)Obsessive Compulsive Disorder Foundation, 1988-present;Borderline Disorders, 2000-present

Positions in Scientific Societies
Chairperson, Committee on Biological Aspects of Child Psychiatry, American Academy of Child Psychiatry,1979‑1982
Council Member, American Psychopathological Association,1986‑1989
Council Member, American College of Neuropsychopharmacology, 1987‑1989
Program Chair, American College of Neuropsychopharmacology,1994

President of Society for Research in Child and Adolescent Psychopathology 199-1993
President, American Psychopathological Association,
1998

Major Fields of Research Interest:

Psychiatric Diagnosis
Hyperactive Children
Biological Aspects of Child Psychiatry
Pediatric Psychopharmacology
Obsessive Compulsive Disorder
Childhood Psychoses

Home Address: 3010 44th Place, N.W.
Washington, D.C. 20016

PUBLICATIONSBOOKS

Rapoport JL (Ed.) Childhood Onset of >Adult= Psychopathology: Clinical and Research Advances. American Psychiatric Press, Inc., Washington, D.C. 2000.

CHAPTERS AND BOOK REVIEWS:

Thompson P, Mega MS, Vidal C, Rapoport JL, Toga AW: Detecting disease-specific patterns of brain structure using cortical pattern matching and a population-based probabilistic brain atlas. In: Insana MF, Leahy RM (eds) IPMI 2001, LNCS 2082, Springer-Verlag Berlin Heidelberg, pp.488-501, 2001.

Kumra S, Nicolson R, Rapoport JL: Childhood-Onset Schizophrenia: research update. In: Zipursky RB, SchulzSC, (eds.) The Early Stages of Schizophrenia , American Psychiatric Press, Washington, D.C. pp. 161-190, 2002.

Nicolson R, Rapoport JL: Neurobiology of childhood schizophrenia and related disorders. In: Martin A, Scahill L, Charney DS, and Leckman JF (eds.) Pediatric Psychopharmacology: Principles and Practice, Oxford University Press, pp. 184-194, 2003.

Freeman JB, Garcia AM, Swedo SE, Rapoport JL, Fucci CM, Leonard HL: Obsessive-Compulsive Disorder. Chapter in: Wiener JM & Dulcan MK (Editors) Textbook of Child and Adolescent Psychiatry, 3rd Edition. American Psychiatric Publishing, Inc. Washington, D.C. 2003.

Thompson PM, Rapoport JL, Cannon TD, Toga AW. Automated Analysis of Structural MRI Data, In: Schizophrenia: from Neuroimaging to Neuroscience, Lawrie AL, Weinberger D, Johnstone EC [eds.], Oxford University Press, 2004.

Nitin Gogtay, Alexandra Sporn, Judith L. Rapoport:Automated analysis of structural MRI data. In:Schizophrenia: From Neuroimaging to Neuroscience.Editors: Stephen Lawrie, Eve Johnstone and Daniel Weinberger. Oxford University Press, 2004.
Gogtay N, Rapoport JL: The neurobiology of childhoodpsychotic disorders. Chapter in: Charney DS, Nestler EJ (eds): Neurobiology of Mental Illness, 2nd edition. Oxford University Press, 2004.

Gogtay N, Rapoport JL: Other psychotic disorders in childhood and adolescence. In: Findling RL, Schulz SC (Editors), Juvenile-Onset Schizophrenia: Assessment, Neurobiology, and Treatment Hopkins University Press, 2005.

Nitin Gogtay and Judith L. Rapoport. Brain imaging studies in childhood onset schizophrenia. Chapter In: The EarlyCourse of Schizophrenia. Editors: Tonmoy Sharma and Philip Harvey. Oxford University Press, 2005.

Judith L. Rapoport. Psychotherapy and the Single Synapse. In: Psychiatry, sychoanalysis, and the New Biology of Mind. Editor: Eric Kandel, American Psychiatric Press Inc, Washington DC. 2005.
Thompson, PM, Sowell ER, Gogtay N, Giedd JN, Vidal CN, Hayashi KM, Leow A, Nicolson R, Rapoport JL, Toga AW.Structural MRI and brain development. In: Glabus M (ed.)International Review of Neurobiology, 2005.

Freeman JB, Garcia AM, Swedo SM, Rapoport JL, Ng, JS,Leonard HL: Obsessive-compulsive disorder. Chapter in:Essentials of Child and Adolescent Psychiatry, Editors: Mina K. Dulcan and Jerry M. Wiener. American Psychiatric Press, pp. 441-453, 2006.

Gogtay N, Rapoport JL; Childhood Onset Schizophrenia andOther Early Onset Psychotic Disorders. Lewis’s Child andAdolescent Psychiatry: A comprehensive Textbook, FourthEdition (L4). Editors: Andres Martin, M.D. and Fred Volkmar,M.D.; Lippincott Williams and Wilkins, Philadelphia PA,2007.

Rapoport JL and Inoff-Germain G. Unshackling the Slaves ofObsession and Compulsion. Chapter in: The Dana Foundation’s Cerebrum 2007: Emerging Ideas In Brain Science. Editor:Cynthia A Read. Dana Press, New York, 2007

Rapoport,JL & Inoff-Germain, G. Neurobiology and Pharmacotherapy of Obsessive Compulsive Disorder. In Handbook of Contemporary Neuropharmacology,in press.

PEER-REVEIWED PUBLICATIONS:

Rapoport JL: Editorial: The Development ofNeurodevelopmental Psychiatry. Am J Psychiatry 157:159-161, February 2000.

Giedd JN, Rapoport JL, Garvey M, Perlmutter S, Swedo SN:MRI assessment of children with obsessive-compulsive disorder of tics associated with streptococcal infection. Am J Psychiatry, 157:281-283, 2000.

Nopoulos P, Berg S, Castellanos FX, Delgado A, Andreasen NC, Rapoport JL: Developmental Brain Anomalies in Children With Attention Deficit Hyperactivity Disorder. J Child Neurol 15:102-108, 2000.

Usiskin SI, Nicolson R, Lenane M, Rapoport JL: Gabapentin prophylaxis of Clozapine-induced seizures in a patient with childhood-onset schizophrenia. Letter to the Editor, Am J Psychiatry,157:3,482-483,2000.

Nicolson R, Lenane M, Hamburger S, Fernandez T, Bedwell J, Rapoport JL: Lessons from Childhood-Onset Schizophrenia. Brain Research Reviews, 31:147-156, 2000.

Grothe DR, Calis KA, Jacobsen L, Kumra S, DeVane CL, Rapoport JL, Bergstrom RF, Kurtz DL: Olanzapine pharmacokinetics in pediatric and adolescent inpatients with childhood onset schizophrenia. J Clin Psychopharmacology,
20:220‑225, 2000.

Kumra S, Wiggs E, Bedwell J, Smith AK, Arling E, Albus K, Hamburger SD, McKenna K, Jacobsen LK, Rapoport JL, Asarnow RF: Neuropsychological deficits in pediatric patients with childhood-onset schizophrenia and psychotic disorders not otherwise specified. Schizophrenia Research, 42:135-144.2000.

Giedd JN, Rapoport JL, Garvey M, Perlmutter S, Swedo SE:
MRI assessment of children with obsessive‑compulsive disorder or tics associated with streptococcal infection. American Journal of Psychiatry 157:281-283, 2000.

Kumra S, Giedd JN, Vaituzis C, Jacobsen LK, McKenna K, Bedwell J, Hamburger S, Nelson J, Lenane M, Rapoport JL: Childhood-onset psychotic disorders: Magnetic resonance imaging of volumetric differences in brain structure. Am J Psychiatry, 157:1467-1474, 2000.

Nicolson R, Lenane M, Singaracharlu S, Malaspina D, Giedd JN, Hamburger SD, Gochman P, Bedwell J, Thaker GK, Fernandez T, Wudarsky M, Hommer DW, Rapoport JL Premorbid Speech and Language Impairments in Childhood-Onset Schizophrenia: Association with Inherited Indicators of Risk.
Am J Psychiatry, 157:794-800, May, 2000.

Yan W, Guan XY, Green ED, Nicolson R, Yap TK, Zhang J, Jacobsen LK, Krasnewich DM, Kumra S, Lenane MC, Gochman P, Damschroder‑Williams PJ, Esterling LE, Long RT, Martin BM, Sidransky E, Rapoport JL, Ginns EI: Childhood‑onset schizophrenia/autistic disorder and t(1;7) reciprocal translocation: identification of a BAC contig spanning the translocation breakpoint at 7q21.Am J Med Genet (Neuropsychiatric Genet), 96:749‑753,2000.

Usiskin SI, Nicolson R, Lenane M, Rapoport JL: Retreatment with clozapine after erythromycin‑induced neutropenia.Am J Psychiatry, 157:1021, 2000.

Rapoport JL: Inoff-Germain G, Practitioner review: Treatment of Obsessive-Compulsive Disorder in children and adolescents. J Child Psychiat Psychol, 41:419-431, 2000.

Alfaro CL, Nicolson R, Lenane M, Rapoport JL: Letter to the Editor: Carbamazine and/or Fluvoxamine drug interaction with risperidone in a patient on multiple psychotropic medications. The Annals of Pharmacotherapy, January 34:122-123,2000.

Nicolson R, Swedo SE, Lenane M, Bedwell J, Wudarsky M,
Gochman P, Rapoport JL: An open trialplasma exchange in childhood-Onset Obsessive-Compulsive Disorder without Post
-Streptococcal Exacerbations. Journal of the AmericanAcademy of Child and Adolescent Psychiatry Oct 39:1313 -1315, 2000.

Karp BI, Garvey M, Jacobsen LK, Frazier JA, Hamburger SD,Bedwell JS, Rapoport JL: Abnormal neurologic maturationin Adolescents with early-onset schizophrenia. Am JPsychiatry, 158:118-122, 2001.

Rapoport JL, Inoff-Germain G: Update on Childhood-OnsetSchizophrenia. Current Psychiatry Reports, 2:410-415,2000.

Rapoport JL, Inoff-Germain G, Weissman MM, Greenwald S, Narrow WE, Jensen PS, Lahey BB, Canino G: Childhoodobsessive-compulsive disorder in the NIMH MECA study:Parent versus child identification of cases. Journal ofAnxiety Disorders 4:535-548, 2000.

Castellanos X, Giedd JN, Berquin PC, Walter JM, Sharp W,TranTL, Vaituzis AC, Blumenthal J, Nelson J, Bastain T, Zijdenbos J, Evans,AC, Rapoport JL: Quantitative Brain Magnetic Resonance Imaging in Girls With Attention-Deficit/Hyperactivity. Arch Gen Psychiatry, 58:289-289, 2001.

Gogate N, Giedd J, Janson K, Rapoport JL: Brain imagingin normal and abnormal brain development - Newperspectives for child psychiatry. Clinical NeuroscienceResearch, 1 (2001) 283-290.

Wudarsky M, Lenane M, Rapoport JL: Childhood-onsetSchizoprenia. In (Lieberman & Murray, eds) Comprehensive Care of Schizophrenia, Martin Dunitz, 2001,pp.283-290.

Kumra S, Sporn A, Homner DW, Nicolson R, Thaker G, IsraelE, Lenane M, Bedwell J, Jacobsen LK, Gochman P,Rapoport JL: Smooth pursuit eye-tracking impairment inchildhood-onset psychotic disorders. American Journal of Psychiatry,158:1291-1298, 2001.

Nicolson R, Lenane M, Brookner F, Gochman P, Kumra S, Spechler L, Giedd JN, Thaker GK, Wudarsky M, Rapoport JL:Children and adolescents with psychotic disorder not otherwise specified: A two to eight year followup.Comprehensive Psychiatry, 42:319-325,2001.
Rapoport JL, Castellanos FX, Gogate N, Janson K, Kohler S, Nelson P: Imaging normal and abnormal braindevelopment - New Perspectives for Child Psychiatry. Australian and New Zealand Journal of Psychiatry,35:272- 281, 2001.
Frazier JA, Glassner-Cohen L, Jacobsen L, Grothe D,Flood J, Baldessarini RJ, Piscitelli S, Kim GS, Rapoport JL. Clozapine pharmacokinetics in children and adolescentswith childhood-onset schizophrenia. J ClinPsychopharmacology, 23:87-91, 2003.

Thompson PM, Vidal C, Giedd JN, Gochman P, BlumenthalJ,Nicolson R, Toga AW, Rapoport JL: Mapping adolescentbrain change reveals dynamic wave of accelerated gray matter loss in very early-onset schizophrenia. PNAS, 98:20, 11650-11655, September 25, 2001.

Calderoni D, Wudarsky M, Bhangoo R, Dell ML Nicolson R,Hamburger SD, Gochman P, Lenane M, Rapoport JL, Leibenluft E: Differentiating childhood-onsetschizophrenia from psychotic mood disorders. JAACAP, 40:1190-1196, 2001.

Chung MK, Worsley KJ, Paus T, Cherif C, Collins DL, Giedd JN, Rapoport JL, Evans AC: A unified statisticalapproach to deformation-based morphometry. Neuroimage 14:595-606, 2001.

Gogtay, N; Giedd J; Rapoport JL: Brain development inhealthy, hyperactive and psychotic children. Archives of Neurology. 59:1244-1248, 2002.

Rapoport JL: Books, Journals, New Media: Letter to the Editor, “Political Correctness - PC, MD: How Political Correctness is Corrupting Medicine, by Sally Satel, 285 pp, Basic Books, New York, New York, 2000”JAMA, 286:2738-2739, 2001.

Sporn A, Rapoport JL: Mini Review: Childhood-Onset Schizophrenia. Child and Adolescent Psychopharmacology 6:1-6, April 2001.

Castellanos FX, Lee PP, Sharp, W, Jeffries NO, Greenstein, DK, Clasen LS, Blumenthal JD, James RS, Ebens CL, Walter JM, Zijdenbos A, Evans AC, Giedd JN, Rapoport JL. Developmental Trajectories of Brain Volume Abnormalities in Attention-Deficit/Hyperactivity Disorder. JAMA 288:1740-1748, 2002.

Bastain TM, Lewczyk CM, Sharp WS, James RS, Long RT,
Eagan PB, Ebens CL, Meck JM, Chan WY, Sidransky ER, Rapoport JL, Castellanos FX. Cytogenetic abnormalities in attention-deficit/hyperactivity disorder. JAACAP, 14:7, 806-810, 2002.

Hui Liu, Simon C. Heath, Christina Sobin, J. Louw
Roos, Brandi L. Galke, Maude L. Blundell, Marge Lenane, Brian Robertson, Ellen M. Wijsman, Judith L. Rapoport, Joseph A. Gogos, and Maria Karayiorgou.
Genetic Variation at the 22q11 PRODH2/DGCR6 locus presents an unusual pattern and increases susceptibility to schizophrenia. Proc Natl Acad Sci USA 99 (6), 3717-3722 (2002).

Alfaro CL, Wudarsky M, Nicolson R, Gochman R, Sporn A, Lenane M, Rapoport JL: Correlation of antipsychotic and prolactin concentrations in children and adolescents acutely treated with Haloperidol, Clozapine, or Olanzapine. Journal of Child and Adolescent Psychopharmacology, 12:83-91,2002.

Gogtay N, Sporn A, Alfaro CL, Mulqueen A, Rapoport JL: Clozapine induced akathisia in children with schizophrenia. J Child Adolesc Psychopharmacology, 12:347- 349, 2003.

Castellanos FX, Rapoport JL: Effects of caffeine on development and behavior in infancy and childhood: a review of the published literature. Food and Chemical Toxicology, 40:1235-1242, 2002.

Rapoport JL, Swedo S: Obsessive-Compulsive Disorder.
Chapter in: Rutter M, Taylor E, Child and Adolescent Psychiatry, 4th Edition. Chapter 35, pp. 571-592,
Blackwell Publishing, Oxford UK, 2002.

Keller A, Castellanos FX, Vaituzis AC, Jeffries NO, Giedd JN, Rapoport JL: Progressive loss of cerebellar volume in childhood onset schizophrenia. Am J Psychiatry, 160:128- 133, 2003.

Sharp W, Gottesman RF, Greenstein DK, Ebens CL,Rapoport JL, Castellanos FX: Monozygotic Twins Discordant for Attention-Deficit/Hyperactivity Disorder: Ascertainment and Clinical Characteristics. JAACAP,42:93-97, 2002.
Rapoport JL, Inoff-Germain G: Responses to methylphenidate in Attention-Deficit/Hyperactivity Disorder and Normal Children: Update 2002. Journal of Attention Disorders 6:Suppl 1,S-57 - S-59, 2002.

Rapoport JL, Castellanos FX, Gogate N, Janson K, Kohler S, Nelson P: Correspondence: Reply to Dr. Halasz. Aust N Z J Psychiatry. 2002 Aug;36:563.

Liu H, Abecasis GR, Heath SC, Knowles A, Demars S, Chen YJ, Roos JL, Rapoport JL, Gogos JA, Karayiorgou M. Genetic variation in the 22q11 locus and susceptibility to schizophrenia. Proc Natl Acad Sci U S A. 99: 16859-16864, December 24, 2002.

Chung MK, Worsley KJ, Robbins S, Paus T, Taylor J, Giedd JN, Rapoport JL, Evans AC: Deformation-based surface morphometry applied to gray matter deformation. Neuroimage, 18:198-213, 2003.

Gogtay N, Sporn A, Clasen LS, Greenstein D, Giedd JN, Lenane M, Gochman PA,Zijdenbos A, and Rapoport JL. Structural Brain MRI Abnormalities in Healthy Siblings of Patients With Childhood-Onset Schizophrenia. Am J Psychiatry, 160:569-571, 2003.

Nicolson R, Brookner F, Lenane M, Gochman P, Ingraham LJ, Egan MF, Kendler KS, Picker D, Weinberger DR, Rapoport JL: Parental schizophrenia spectrum disorders in childhood- onset and adult-onset schizophrenia. Am J Psychiatry, 160:490-495, 2003.

Keller A, Jeffries NO, Blumenthal J, Clasen LS, Liu H, Giedd JN, Rapoport JL: Corpus callosum development in childhood-onset schizophrenia. Schizophrenia Research, 62:105-114, 2003.

Inoff-Germain G, Rodriguez RS, Torres-Alcantara S, Diaz Jimenez M, Swedo SE, Rapoport JL: An immunological marker D8/17) associated with rheumatic fever as a predictor of childhood psychiatric disorders: A prospective study. Journal of Child Psychololgy and Psychiatry and Allied Disciplines, in 44:782-790, 2003.

Mathalon DH, Rapoport JL, Davis KL, Krystal JH.Neurotoxicity, neuroplasticity, and magnetic resonance imaging morphometry. Arch Gen Psychiatry. Aug 60(8):846-8, 2003.

Castellanos FX, Sharp W, Gottesman R, Greenstein D, Giedd JN, Rapoport JL: Anatomic brain abnormalities in monozygotic twins discordant for attention- deficit/hyperactivity disorder. Am J Psychiatry, Sep;160(9):1693-6, 2003.

Sporn A, Gogtay N, Ortiz-Aguayo R, Alfaro CL, Tossell J, Lenane M, Gochman P, Rapoport JL: Clozapine-induced neutropenia in children: Management with lithium carbonate. J Child Adoles Psychopharm,13:401-404,2003.

Sporn AL, Greenstein DD, Gogtay N, Jeffries NO, Lenane M,Gochman P, Clasen LS, Blumenthal J, Giedd JN, Rapoport JL. Progressive brain volume loss during adolescence in childhood onset schizophrenia. Am J Psychiatry, 160:2181- 2189, 2003.

Sporn A, Addington A, Reiss AL, Dean M, Gogtay N, Potocnik U, Greenstein D, Hallmayer J, Gochman P, Lenane M, Baker N,Tossell J and Rapoport JL. 22q11 deletion syndrome in childhood onset schizophrenia: an update. Scientific Correspondence, Mol Psychiatry, 1-2, 2003.

Gogtay N, Sporn A, Clasen L, Nugent T, Greenstein D, Nicolson R, Giedd, J, Lenane M, Gochman P, Evans A, and Judith L. Rapoport: Comparison of progressive cortical gray matter loss in childhood-onset schizophrenia with that in childhood-onset atypical psychoses. Arch Gen Psychiatry, 61:17-22, 2004.

Stayer C, Sporn A, Gogtay N, Tossell J,Lenane M, Gochman P, Rapoport JL, Looking for Childhood-Onset Schizophrenia: Case Series of False Positives. J Am Acad Child Adolesc Psychiatry 43:1026-1029, 2004.

Arcos-Burgos M, Castellanos FX, Konecki D, Lopera F, Pineda D, Palacio JD, Rapoport JL, Berg K, Bailey-Wilson J, Muenke M. Pedigree disequilibrium test (PDT) replicates association and linkage between DRD4 and ADHD in multigenerational and extended pedigrees from a genetic isolate. Molecular Psychiatry, 9:252-259,2004.

Sporn A, Addington A, Gogtay N, Gornick M, Clasen L, Greenstein D, Ordoñez A, Tossell J, Gochman P, Lenane M, Rapoport JL. Pervasive Developmental Disorder and Childhood Onset Schizophrenia: Comorbid Disorder or a Phenotypic Variant? Biological Psychiatry, 55:989-94, 2004.

Addington AM, Gornick M, Sporn A, Gogtay N, Greenstein D, Lenane M, Gochman P, Baker N, Balkissoon R, Weinberger DR, Straub RE, Rapoport JL. Polymorphisms in the 13q33.2 gene G72/G30 are associated with childhood onset schizophrenia and psychosis not otherwise specified. Biol Psychiatry. 55:976-80, 2004.

Gogtay N, Giedd JN, Lusk L, Hayashi KM, Greenstein D, Vaitiuzis D, Nugent TF III, Herman DH, Clasen L, Toga AT, Rapoport JL, Thompson PM. Dynamic mapping of human cortical development during childhood through early adulthood. PNAS, 101:8174-8179, 2004.

Tossell JW, Greenstein D, Davidson A, Job S, Gochman P, Lenane M, Gogtay N, Sporn A, Rapoport, JL. Stimulant Drug Treatment in Childhood-Onset Schizophrenia with Comorbid ADHD. J Child Adolesc Psychopharm, 14(3):448-454, 2004.

Gochman P, Greenstein D, Sporn A, Gogtay N, Nicolson R, Keller A, Lenane M, Brookner F, Rapoport JL. Childhood Onset Schizophrenia: Familial Neuropsychological Measures. Schizophrenia Research, 71:43-47, 2004.

Swedo SE, Leonard HL, Rapoport JL. The pediatric autoimmune neuropsychiatric disorders associated with streptococcal infection (PANDAS) subgroup: separating fact from fiction.
Pediatrics, 113,907-11, 2004.

Bobb A, Castellanos FX, Addington A, Rapoport JL: Molecular genetic studies of ADHD:1991 to 2004 Am J Med Genet Sep 29, 2004.

Arcos-Burgos M, Castellanos FX, Pineda D, Lopera F, David Palacio J, Guillermo Palacio L, Rapoport JL, Berg K, Bailey-Wilson JE, Muenke M. Attention-Deficit/HyperactivityDisorder in a Population Isolate: Linkage to Loci at 4q13.2,5q33.3, 11q22, and 17p11. Am J Hum Genet. 2004 Oct 20;75(6).

Thompson PM, Hayashi KM, Sowell ER, Gogtay N, Giedd JN, Rapoport JL, de Zubicaray GI, Janke AL, Rose SE, Semple J, Doddell DM, Wang Y, van Erp TGM, Cannon TD, Toga AW Mapping cortical change in Alzheimer's disease, braindevelopment, and schizophrenia. Neuroimage 23 S2-S18,2004.

Addington AM, Gornick M, Duckworth J, Sporn A, Gogtay N,Bobb A, Greenstein D, Lenane M, Gochman P, Baker N, Balkissoon R, Vakkalanka RK, Weinberger DR, Rapoport JL, and Straub RE. GAD1 gene (2q31.1), which encodes glutamic acid decarboxylase(GAD67), is associated with childhood onset schizophrenia and cortical gray matter loss. Mol Psychiatry 1-8,2004.

Palacio JD, Castellanos FX, Pineda DA, Lopera F, Arcos-Burgos M, Quiroz YT, Henao GC, Puerta IC, Ramirez DL,Rapoport JL, Bailey-Wilson J, Berg K, Muenke M. Attention- deficit/hyperactivity disorder and comorbidities in 18 paisa Columbian multigenerational families. JAACAP 43:1506- 1515, 2004.

Rapoport JL: Childhood onset schizophrenia. A progressive neurodevelopmental disorder. Int J Neuropsychoph Suppl. 1 Jun 2004 7:S22-S22.

Rapoport JL, Gogtay N, Sporn A. A progressive neurodevelopmental disorder. Int J Neuropsychoph Suppl 1 Jun 2004, 7:S42-S42.

Rapoport JL, Addington A, Frangou S. The Neurodevelopmental Model of Schizophrenia: Update 2005. (Invited Review Special Commentary). Mol Psychiatry, 1-16, 8 February, 2005.

Sporn A, Greenstein D, Gogtay N, Sailer F, Hommer D, Rawlings R, Nicolson R, Egan MF, Lenane M, Gochman P, Weinberger DR, Rapoport JL. Childhood Onset Schizophrenia: Smooth Pursuit Eye-Tracking Dysfunction in Family Members, Schiz Res,73:243-252, 2005.

Bobb AJ, Addington AM, Sidransky E, Gornick MC, Lerch JP, Greenstein DK, Clasen LS, Sharp WS, Inoff-Germain G,Wavrant-DeVrièze F, Arcos-Burgos M, Straub RE, HardyJA, Castellanos FX, and Rapoport JL. Support for Association Between ADHD and Two Candidate Genes: NET1 and DRD1. Am J Med Genet Part B (Neuropsychiatric Genetics)
134B:67-72, 2005.

Gochman PA, Greenstein D, Sporn A, Gogtay N, Keller B, and Rapoport JL: IQ stabilization in Childhood-Onset Schizophrenia. Schiz Res, 2005, May 21.

Stayer C, Sporn A, Gogtay N, Tossell J, Lenane M, Gochman P, Greenstein D, Sharp W, Rapoport JL. Multidimensionally- impaired: the good news. J Child Adolesc Psychopharmacology. 15:3 510-519, 2005.

Sporn AL, Bobb AJ, Gogtay N, Stevens H, Greenstein DK, Clasen LS, Tossell JW, Nugent T, Gochman P, Sharp WS, Matai A, Lenane MC, Yanovski JA, Rapoport JL. Hormonal correlates of clozapine-induced weight gain in psychotic children: an explorative study. JAACAP, 44:925-933, 2005.

Gornick MC, Addington AM, Sporn A, Gogtay N, Greenstein D,
Lenane M, Gochman P, Ballkission R, Weinberger DR, Straub R, Rapoport JL. Dysbindin (DTNBP1,6p22.3) is associated with childhood onset psychosis and endophenotypes measured by the Premorbid Adjustment Scale (PAS). J Autism Dev Disorders, Nov 10, 1-8, 2005.

Ordonez AE, Bobb A, Greenstein D, Baker N, Sporn A, Lenane M, Malaspina D, Rapoport JL, Gogtay N. Lack of evidence for elevated obstetric complications in childhood onset schizophrenia. Biol Psychiatry, 58:10-15, 2005.

Vidal CN, Rapoport JL, Hayashi KM; Geaga JA, Sui Y, McLemore LE, Alaghband Y, Giedd JN, Gochman P, Blumenthal J, Gogtay N, Nicolson R, Toga AW, Thompson PM: Dynamically Spreading Frontal and Cingulate Deficits Mapped in Adolescents With Schizophrenia. Arch Gen Psychiatry63:25-34, 2006.

Jacquet H, Rapoport JL, Hecketsweiler B, Bobb A, Thibaut F, Frebourg T, Campion D: Hyperprolinemia is not associated with childhood onset schizophrenia. Am J Med Gen B: Neuropsychiatric Genetics. Jan 2006.

Shaw P, Greenstein D, Lerch J, Clasen L, Lenroot R, Gogtay N, Evans A, Rapoport J, Giedd J. Intellectual ability and cortical development in children and adolescents. Nature, 440:676-679, 30 March 2006.

Shaw P, Lerch J, Greenstein D, Sharp W, Clasen L, Evans A, Giedd J, Castellanos FX, Rapoport J. Longitudinal mapping of cortical thickness and clinical outcome in children and adolescents with attention-deficit/hyperactivity disorder.
Arch Gen Psychiatry, 63:540-549, 2006.

Shaw P, Sporn A, Gogtay N, Overman G, Greenstein D, Gochman P, Tossell J, Lenane J, Rapoport, JL. Childhood-onset schizophrenia. A double-blind, randomized clozapine-olanzapine comparison. Arch Gen Psychiatry, 63:721-730, 2006.
Gogtay N, Nugent TF III, Herman DH, Ordonez A, Greenstein D, Hayashi KM, Clasen L, Toga AW, Giedd JN, Rapoport JL, Thompson PM. Dynamic Mapping of Normal Human Hippocampal Development. Hippocampus, 16:664-672, 2006.
.Mattai AA, Tossell J, Greenstein DK, Addington A, ClasenLS, Gornick MC, Seal J, Inoff-Germain G, Gochman PA, Lenane M, Rapoport JL, Gogtay N. Sleep disturbances in childhood-onset schizophrenia. Schizophr Res. 86:123-129, 2006.

Greenstein D, Lerch J, Shaw WP, Clasen L, Giedd J,Gochman P, Rapoport J, and Gogtay N: Childhood Onset Schizophrenia: Cortical Brain Abnormalities as Young Adults. J Child Psychology and Psychiatry, 47:1003-1012, 2006.

Seal JL, Gornick MC, Gogtay N, Shaw P, Greenstein DK, Coffey M, Gochman PA, Stromberg T, Chen Z, Merriman B, Nelson SF, Brooks J, Arepalli S, Wavrant-De Vrieze F, Hardy J, Rapoport JL, Addington AM. Segmental uniparental isodisomy on 5q32-qter in a patient with childhood-onset schizophrenia. J Med Genet. 2006 Jun 8; [Epub ahead of print]

Addington AM, Gornick MC, Shaw P, Seal J, Gogtay N, Greenstein D, Clasen L, Coffey M, Gochman P, Long R, Rapoport JL: Neuregulin (NRG1, 8p12) and Childhood Onset Schizophrenia: Susceptibility Haplotypes for Diagnosis and Brain Developmental Trajectories. Mol Psychiatry,
10 October 2006, 1-11. (Advance online publication).

Shaw P, Rapoport JL: Decision making about children with psychotic symptoms: using the best evidence in choosing a treatment. J Am Acad Child Adolesc Psychiatry, Nov;45: 1381-1386, 2006.

Stein DJ, Arya M, Pietrini P, Rapoport JL, Swedo SE: Neurocircuitry of disgust and anxiety in obsessive-computer disorder: A positron emission tomography study. Metab Brain Dis July 19; [Epub ahead of print] 2006

Stromberg T, Chen Z, Merriman B, Nelson SF, Brooks J, Arepalli S, Wavrant-De Vrieze F, Hardy J, Rapoport JL, Addington, AM. Segmental uniparental isodisomy on 5q32- qter in a patient with childhood-onset schizophrenia. J Med Genet. Nov 43:887-892, 2006.

Nugent TFIII, Herman DH, Ordonez A, Greenstein, D, Hayashi KM, Lenane M, Clasen L, Jung D, Toga AW, Giedd JN, Rapoport JL, Thompson PM, Gogtay N. Dynamic mapping of hippocampal development in childhood onset schizophrenia. Schizophrenia Research, 2006 Dec 8; [Epub ahead of print].

Gornick MC, Addington A, Shaw P, Bobb AJ, Sharp W, Greenstein D, Arepalli S, Castellanos FX, Rapoport JL:

Association of the dopamine receptor D4 (DRD4) gene 7- repeat allele with children with attention- deficit/hyperactivity disorder (ADHD): An update.
Am J Med Genet B Neuropsychiatr Genet. 2006 Dec 14; [Epub ahead of print]

Mackie S, Shaw P, Lenroot R, Pierson R, Geenstein D, Nugent T, Sharp W, Giedd J, Rapoport J. Cerebellar Development andClinical Outcome in Attention Deficit/Hyperactivity Disorder (ADHD). Am J Psychiatry, 164:647-655, 2007.

Shaw P, Lerch J, Pruessner JC, Taylor K, Rose AB, Greenstein D, Clasen L, Evans A, Rapoport JL, Giedd JN. Cortical morphology in children and adolescents with different apolipoprotein E gene polymorphisms: an observational study. The Lancet, 6:494-500, June 2007.

Gogtay N, Greenstein D, Lenane M, Clasen L, Sharp W, Gochman P, Butler P, Evans A, Rapoport J: Cortical Brain Development in Non-psychotic Siblings of Patients with Childhood Onset Schizophrenia. Arch Gen Psychiatry, 64:772- 780, 2007.

Sporn AL, Vermani A, Greenstein DK Bobb AJ, Spencer EP, Clasen LS, Tossell JW, Stayer C, Gochman PA, Lenane MC, Rapoport JL, Gogtay N. Clozapine Treatment of Childhood Onset Schizophrenia: Evaluation of Efficacy, Adverse Effects, and Long-Term Outcome. JAACAP, in press.

Shaw P, Gornick M, Lerch J, Addington A, Greenstein D, Sharp W, Evans A, Giedd J, Castellanos FX, Rapoport JL: Polymorphisms of the dopamine D4 receptor, clinical outcome and cortical structure in attention-deficit/hyperactivity disorder. Arch Gen Psychiatry, in press.

Gogtay N, Ordonez A, Herman DH, Hayashi KM, Greenstein D,Vaituzis C, Lenane M, Liv Clasen, Sharp W, Giedd JN, Nugent TF III, Toga AW, Leibenluft E, Thompson PM, Rapoport JL:Dynamic Mapping of Cortical Development Before and After the Onset of Pediatric Bipolar Illness. JCPP, in press.

Shaw P, Lerch J, Greenstein D, Sharp W, Clasen L, Evans A, Giedd J, Castellanos FX, Rapoport J. Longitudinal mapping of cortical thickness and clinical outcome in children and adolescents with attention deficit/hyperactivity disorder.
Arch Gen Psychiatry, in press.

Shaw P, Sporn A, Gogtay N, Nicolson R, Overman G, Greenstein D, Gochman P, Tossell J, Lenane J, Rapoport JL.Childhood-onset schizophrenia. A double-blind, randomized clozapine-olanzapine comparison. Arch Gen Psychiatry, in press.

Giedd JN, Molloy EA, Castellanos FX, Jeffries N, Blumenthal JD, Gogtay N, Clasen L, Liu H, Neale M, Keller A, Zijdenbos A, Evans AC, Rapoport JL: The cerebellum: unique developmental characteristics during childhood and adolescence. In preparation.